Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534442 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL24464120 | 0.86 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL8530147 | 0.81 | MAPT (0.56) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL420971 | 0.81 | MAPT (0.56) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL11034340 | 0.81 | MAPT (0.53) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL11034335 | 0.81 | MAPT (0.53) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL1031259 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL9978289 | 0.78 | MAPT (0.69) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL14935499 | 0.78 | MAPT (0.69) | ALDH1A1MAPTCYP19A1KMT2AMEN1 | |
| SCHEMBL11049170 | 0.78 | MAPT (0.69) | ALDH1A1MAPTCYP19A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489547-B1 | A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof | ZENECA LTD (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5280125-A | Chemical process for the preparation of 3-alkylated indole | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0489547-A1 | A process for the preparation of a 3-alkylated indole, intermediates, and a process for the preparation of a derivative thereof | ZENECA LIMITED (GB) | 1992-06-10 | — | — | EP | disclosed |
| US-4264775-A | BY DIAZOTIZATION OF ANILINES, REACTING WITH A VINYL ESTER, AND REACTING WITH A SECONDARY AMINE | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |