Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538648 | 0.79 | HTT (0.41) | SRCPOLBCYSLTR2CYSLTR1KMT2A | |
| SCHEMBL8538406 | 0.75 | GABRA1 (0.42) | SRCKMT2A | |
| SCHEMBL8538797 | 0.75 | CYSLTR2 (0.43) | SRCCYSLTR2CYSLTR1 | |
| SCHEMBL547637 | 0.72 | GRIK1 (0.58) | GRIK1PPM1D | |
| SCHEMBL3647579 | 0.72 | GRIK1 (0.58) | GRIK1PPM1D | |
| SCHEMBL8535772 | 0.71 | PTGDR2 (0.42) | SRCKMT2A | |
| SCHEMBL8540016 | 0.70 | PTGDR2 (0.44) | SRCKMT2A | |
| SCHEMBL8539964 | 0.69 | CYP2C9 (0.49) | SRC | |
| SCHEMBL6950812 | 0.68 | SRC (0.43) | SRCKMT2A | |
| SCHEMBL8536416 | 0.68 | SRC (0.43) | SRCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |