Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3147481 | 0.89 | SRC (0.46) | HTTSRCALDH1A1POLBOPRM1 | |
| SCHEMBL8538797 | 0.88 | CYSLTR2 (0.43) | SRCCYSLTR2CYSLTR1 | |
| SCHEMBL8538406 | 0.85 | GABRA1 (0.42) | HTTSRCALDH1A1GAAGABRA1 | |
| SCHEMBL8539102 | 0.79 | TSHR (0.50) | HTTSRCALDH1A1POLBGAA | |
| SCHEMBL8534617 | 0.79 | GRIK1 (0.36) | SRCPOLBCYSLTR2CYSLTR1KMT2A | |
| SCHEMBL8536459 | 0.78 | SRC (0.43) | SRCALDH1A1POLBGAALMNA | |
| SCHEMBL6950812 | 0.78 | SRC (0.43) | HTTSRCGAAGABRA1GABRB2 | |
| SCHEMBL23116476 | 0.77 | GABRA1 (0.41) | ALDH1A1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8535827 | 0.76 | BACE1 (0.43) | SRC | |
| SCHEMBL5570575 | 0.76 | LMNA (0.48) | ALDH1A1POLBOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |