Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | USP5 | P45974 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381919 | 0.89 | HDAC1 (0.56) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| SCHEMBL10884944 | 0.84 | SMN1; SMN2 (0.88) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| SCHEMBL8537176 | 0.83 | MMP2 (0.52) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| SCHEMBL6832508 | 0.80 | LCK (0.57) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| SCHEMBL12670300 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2MMP2MMP9MMP8CHEK2 | |
| SCHEMBL203627 | 0.78 | LCK (0.59) | MMP2MMP9MMP8CHEK2CYP2E1 | |
| Fenbufen SCHEMBL11329267 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| Fenbufen SCHEMBL25117 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A | |
| SCHEMBL5696420 | 0.78 | FFAR1 (0.62) | FFAR1CYP2E1CYP2A6CYP2B6ACMSD | |
| SCHEMBL10353454 | 0.78 | NR4A2 (0.81) | SMN1; SMN2FFAR1LMNACYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |