Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534716 | 1.00 | HRH3 (0.57) | HRH3KMT2AMEN1TEAD1SMN1; SMN2 | |
| SCHEMBL8532860 | 0.86 | HRH3 (0.56) | HRH3KMT2AMEN1LTA4HKDM4E | |
| SCHEMBL8532857 | 0.86 | HRH3 (0.56) | HRH3KMT2AMEN1LTA4HKDM4E | |
| SCHEMBL8533991 | 0.84 | HRH3 (0.58) | HRH3KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL8533993 | 0.84 | HRH3 (0.58) | HRH3KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL28842288 | 0.83 | HRH3 (0.52) | HRH3KMT2AMEN1TEAD1SMN1; SMN2 | |
| SCHEMBL27805654 | 0.82 | LTA4H (0.62) | HRH3KMT2AMEN1SMN1; SMN2LTA4H | |
| SCHEMBL3022632 | 0.82 | HRH3 (0.57) | HRH3KMT2AMEN1TEAD1SMN1; SMN2 | |
| SCHEMBL8084041 | 0.81 | HRH3 (0.53) | HRH3KMT2AMEN1TEAD1SMN1; SMN2 | |
| SCHEMBL8587005 | 0.79 | HRH3 (0.48) | HRH3KMT2ATEAD1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757669-B1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0757669-A1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029148-A1 | O-ACYL-4-PHENYL-CYCLOHEXANOLS, THEIR SALTS, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND THEIR USE, AS WELL AS A METHOD OF PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1995-11-02 | — | — | WO | disclosed |