Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22416704 | 0.84 | RAB9A (0.66) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL15609584 | 0.83 | RAB9A (0.65) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL22416771 | 0.82 | GLA (0.68) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL6160168 | 0.82 | RAB9A (0.66) | RAB9AALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL8534533 | 0.82 | RAB9A (0.63) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL5948139 | 0.82 | GLA (0.74) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL15610559 | 0.81 | RAB9A (0.65) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL23014104 | 0.81 | ALDH1A1 (0.77) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL1083633 | 0.81 | MEN1 (0.77) | RAB9AALDH1A1HPGDSMN1; SMN2GLA | |
| SCHEMBL2825416 | 0.81 | MAPT (0.69) | RAB9AALDH1A1HPGDSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |