Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 3/20 | 0.36 |
| ▸ | CCKBR | P32239 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537694 | 1.00 | DRD4 (0.40) | DRD4DRD2CYP19A1CA12CA2 | |
| SCHEMBL8534607 | 0.86 | DRD4 (0.42) | DRD4DRD2CYP19A1CA12CA2 | |
| SCHEMBL8534606 | 0.86 | DRD4 (0.42) | DRD4DRD2CYP19A1CA12CA2 | |
| SCHEMBL8537317 | 0.84 | CCKBR (0.40) | CYP19A1LMNAPOLBMAPTCCKAR | |
| SCHEMBL8537321 | 0.84 | CCKBR (0.40) | CYP19A1LMNAPOLBMAPTCCKAR | |
| SCHEMBL8538046 | 0.79 | CCKBR (0.41) | LMNAPOLBMAPTCCKARCCKBR | |
| SCHEMBL8538044 | 0.79 | CCKBR (0.41) | LMNAPOLBMAPTCCKARCCKBR | |
| SCHEMBL8537837 | 0.77 | KDM4E (0.42) | LMNACCKBR | |
| SCHEMBL8535418 | 0.77 | CCKBR (0.47) | CCKARCCKBR | |
| SCHEMBL8535225 | 0.77 | PDE10A (0.39) | LMNAPOLBMAPTCCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |