Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.41 |
| ▸ | CCKAR | P32238 | 7/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538046 | 1.00 | CCKBR (0.41) | CCKBRCCKARADRA1DADRA1AADRA1B | |
| SCHEMBL8537837 | 0.89 | KDM4E (0.42) | CCKBRLMNA | |
| SCHEMBL8537840 | 0.89 | KDM4E (0.42) | CCKBRLMNA | |
| SCHEMBL8532891 | 0.85 | ALDH1A1 (0.51) | CCKBRCCKARLMNA | |
| SCHEMBL8532893 | 0.85 | ALDH1A1 (0.51) | CCKBRCCKARLMNA | |
| SCHEMBL8535418 | 0.85 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL8535416 | 0.85 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL8538016 | 0.84 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL8538017 | 0.84 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL8538174 | 0.83 | CCKBR (0.42) | CCKBRCCKARLMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |