Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | IGF1R | P08069 | 1/20 | 0.65 |
| ▸ | MET | P08581 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.60 |
| ▸ | GABRP | O00591 | 1/20 | 0.60 |
| ▸ | GABRD | O14764 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27597866 | 0.88 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL21439506 | 0.85 | TP53 (0.74) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL28386254 | 0.85 | NPSR1 (0.74) | SMN1; SMN2TP53NPSR1NPC1MEN1 | |
| SCHEMBL10646231 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL10646985 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL8792509 | 0.85 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL13302221 | 0.84 | NPSR1 (0.72) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL15979987 | 0.83 | CTNNB1 (0.72) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL2980233 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TP53NPSR1IGF1RMET | |
| SCHEMBL1563040 | 0.83 | TUBB1 (0.78) | SMN1; SMN2TP53NPSR1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149419-B1 | ACYLINDOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-17 | — | — | EP | claimed |
| US-4708961-A | ANTICOAGULANTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1987-11-24 | — | — | US | claimed |
| EP-0149419-A1 | Acylindole derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1985-07-24 | — | — | EP | claimed |
| JP-60072861-A | — | — | None | — | — | JP | disclosed |
| JP-61047462-A | — | — | None | — | — | JP | disclosed |
| EP-3774767-B1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12152016-B2 | Aryl hydrocarbon receptor modulators and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| US-20230278986-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230278986-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230278986-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-11634408-B2 | Aryl hydrocarbon receptor modulators and uses thereof | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-RE32761-E | ANALGESICS, ANTIRHEUMATIC AND ANTIINFLAMMATORY AGENT | STERLING DRUG INC. (US) | 1988-10-04 | — | — | US | disclosed |
| EP-0149419-B1 | ACYLINDOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-17 | — | — | EP | disclosed |
| US-4708961-A | ANTICOAGULANTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4634776-A | ANALGESIC, ANTIRHEUMATIC, ANTIINFLAMMATORY | STERLING DRUG, INC. (US) | 1987-01-06 | — | — | US | disclosed |
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | disclosed |
| JP-S6147462-A | NOVEL ACYLINDOLE DERIVATIVE AND BLOOD PLATELET AGGLUTINATION INHIBITOR CONTAINING SAID COMPOUND AS ACTIVE CONSTITUENT | NIPPON ZOKI PHARMACEUT CO LTD | 1986-03-07 | — | — | JP | disclosed |
| EP-0171037-A2 | 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof | STERLING WINTHROP INC. (US) | 1986-02-12 | — | — | EP | disclosed |
| EP-0149419-A1 | Acylindole derivatives and pharmaceutical compositions containing them | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| JP-S6072861-A | NOVEL ACYLINDOLE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME | NIPPON ZOKI PHARMACEUT CO LTD | 1985-04-24 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634408-B2 | Aryl hydrocarbon receptor modulators and uses thereof | AHR, ARNT, NR4A1 | SMN1; SMN2 4031/4885TP53 1653/4885NPSR1 275/4885 |
| US-20230278986-A1 | ARYL HYDROCARBON RECEPTOR MODULATORS AND USES THEREOF | AHR, ARNT, NR4A1 | SMN1; SMN2 4063/4885TP53 1611/4885NPSR1 267/4885 |
| US-12152016-B2 | Aryl hydrocarbon receptor modulators and uses thereof | AHR, ARNT, NR4A1 | SMN1; SMN2 4031/4885TP53 1653/4885NPSR1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.