SCHEMBL8534997

SCHEMBL8534997

CCOC(=O)OC1CCN(CCS)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
PKM P14618 1/20 0.37
NFKB1 P19838 1/20 0.37
THPO P40225 1/20 0.37
HIF1A Q16665 1/20 0.37
CARM1 Q86X55 1/20 0.37
PRMT6 Q96LA8 1/20 0.37
GAA P10253 1/20 0.37
BCHE P06276 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
THRB P10828 2/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
GMNN O75496 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9330353 0.82 SCN1A (0.49) ALDH1A1MAPTMEN1KMT2ACHRM3
SCHEMBL1078049 0.79 ALDH1A1 (0.57) GAAALDH1A1MAPTLMNASOAT1
SCHEMBL4640870 0.79
SCHEMBL8552607 0.76 BCHE (0.35) TP53CYP3A4GAABCHEALDH1A1
SCHEMBL8709003 0.76 CHRM4 (0.47) CYP1A2CYP2D6GAAALDH1A1CHRM3
SCHEMBL8708999 0.76 CHRM4 (0.47) CYP1A2CYP2D6GAAALDH1A1CHRM3
SCHEMBL8552348 0.75 BCHE (0.35) CYP3A4GAABCHEALDH1A1SOAT1
SCHEMBL22138607 0.74 NPC1 (0.38) CARM1PRMT6
SCHEMBL3949872 0.74 HRH3 (0.44) ALDH1A1
SCHEMBL305155 0.74 ALDH1A1 (0.50) CYP2D6ALDH1A1THRBLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868900-A1 Composition and method for permanent hair waving Wella Aktiengesellschaft (DE) 1998-10-07 EP disclosed