Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552607 | 0.81 | BCHE (0.35) | BCHEALDH1A1GAASOAT1CHRM4 | |
| SCHEMBL8356716 | 0.79 | MAPT (0.51) | ALDH1A1KDM4ESMN1; SMN2GAACYP2C19 | |
| SCHEMBL4640870 | 0.76 | — | — | |
| SCHEMBL1078049 | 0.76 | ALDH1A1 (0.57) | ALDH1A1GAASOAT1PPM1BPTPN1 | |
| SCHEMBL9330353 | 0.75 | SCN1A (0.49) | ALDH1A1SMN1; SMN2SOAT1CHRM4 | |
| SCHEMBL8534997 | 0.75 | TP53 (0.37) | BCHEALDH1A1GAASOAT1CYP3A4 | |
| SCHEMBL3949872 | 0.71 | HRH3 (0.44) | ALDH1A1 | |
| SCHEMBL305155 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2CYP2C19SOAT1 | |
| SCHEMBL8375449 | 0.70 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2GAACYP2C19SOAT1 | |
| SCHEMBL8624627 | 0.70 | GAA (0.34) | BCHEALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |