Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669800 | 0.80 | SLC18A3 (0.51) | OPRM1OPRD1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10295475 | 0.80 | OPRM1 (0.64) | OPRM1OPRD1 | |
| SCHEMBL12314083 | 0.80 | OPRM1 (0.64) | OPRM1OPRD1 | |
| SCHEMBL522190 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL29649871 | 0.79 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1721954 | 0.78 | SLC6A2 (0.55) | OPRM1OPRD1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL633352 | 0.78 | SLC6A2 (0.55) | OPRM1OPRD1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL633351 | 0.78 | SLC6A2 (0.55) | OPRM1OPRD1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL12314095 | 0.76 | DRD3 (0.58) | — | |
| SCHEMBL10295474 | 0.76 | DRD3 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819126-A1 | BIPHENYLAMIDE DERIVATIVES AS 5HT 1D? ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031508-A1 | BIPHENYLAMIDE DERIVATIVES AS 5HT1D ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-10-10 | — | — | WO | disclosed |