Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536765 | 0.84 | ALDH1A1 (0.44) | KDM4EALDH1A1SMN1; SMN2HPGDERCC5 | |
| SCHEMBL1247973 | 0.79 | MAPT (0.48) | KDM4ECCR9ALDH1A1HPGDMAPT | |
| SCHEMBL31536078 | 0.79 | MAPT (0.48) | KDM4ECCR9ALDH1A1HPGDMAPT | |
| SCHEMBL12458001 | 0.77 | TSHR (0.59) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9632759 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDTDP1 | |
| SCHEMBL17145456 | 0.74 | KDM4E (0.40) | KDM4EL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL8533603 | 0.74 | HTT (0.51) | KDM4EL3MBTL1SMN1; SMN2HPGDGAA | |
| SCHEMBL20312714 | 0.73 | ALDH1A1 (0.35) | KDM4EL3MBTL1ALDH1A1HPGDTDP1 | |
| SCHEMBL16199543 | 0.73 | MAPT (0.40) | L3MBTL1ALDH1A1SMN1; SMN2HPGDMAPT | |
| SCHEMBL11912047 | 0.73 | KDM4E (0.39) | KDM4EL3MBTL1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |