Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535194 | 0.84 | KDM4E (0.40) | ALDH1A1ALOX15KDM4EHPGDKMT2A | |
| SCHEMBL31536078 | 0.79 | MAPT (0.48) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL1247973 | 0.79 | MAPT (0.48) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL8847207 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL9632759 | 0.78 | ALDH1A1 (0.43) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL8847256 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL12458001 | 0.77 | TSHR (0.59) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL16199543 | 0.77 | MAPT (0.40) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| Water SCHEMBL29221157 | 0.76 | ALDH1A1 (0.44) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 | |
| SCHEMBL18000415 | 0.76 | TSHR (0.41) | ALDH1A1ALOX15KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |