SCHEMBL8535231

SCHEMBL8535231

O=C1CCCC(S(=O)(=O)C2CCCC(=O)C2)C1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.35
TRIM24 O15164 2/20 0.35
TRIM33 Q9UPN9 2/20 0.35
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10033899 0.82 THRB (0.37) MAPTTHRBTRIM24TRIM33ALDH1A1
SCHEMBL28541809 0.82 MAPT (0.34) MAPTTHRBTRIM24TRIM33ALDH1A1
Ammonia Solution, Strong SCHEMBL5191934 0.80 THRB (0.36) MAPTTHRBTRIM24TRIM33
SCHEMBL20550187 0.80 THRB (0.36) MAPTTHRBTRIM24TRIM33
SCHEMBL20550163 0.74 THRB (0.36) MAPTTHRB
SCHEMBL3387151 0.73 MAPT (0.50) MAPTALDH1A1
SCHEMBL28867094 0.70
SCHEMBL7877671 0.69 TRIM24 (0.35) TRIM24TRIM33ALDH1A1
SCHEMBL14441603 0.69 TRIM24 (0.42) MAPTTHRBTRIM24TRIM33ALDH1A1
SCHEMBL8654266 0.68 LMNA (0.41) THRBTRIM24TRIM33ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5804347-A POLYESTER MITA INDUSTRIAL CO., LTD. (JP) 1998-09-08 US disclosed
EP-0747774-A2 Electrophotographic toner and contact development method using the toner MITA INDUSTRIAL CO., LTD. (JP) 1996-12-11 EP disclosed