Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909693 | 0.84 | EPHX1 (0.42) | HPGDEPHX1KMT2AEPHX2LMNA | |
| SCHEMBL8106988 | 0.83 | HPGD (0.42) | HPGDEPHX1KMT2AEPHX2LMNA | |
| SCHEMBL1916162 | 0.81 | LMNA (0.53) | HPGDEPHX1KMT2AALDH1A1EPHX2 | |
| Cyclohexane SCHEMBL14673180 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL363901 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL31332587 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| Cyclohexane SCHEMBL7091110 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| Cyclohexane SCHEMBL1245516 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| Cyclohexane SCHEMBL11035387 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL28568368 | 0.80 | EPHX1 (0.50) | HPGDEPHX1KMT2AEPHX2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |