Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483127 | 0.88 | TMEM97 (0.47) | MCHR1TMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL11589105 | 0.79 | POLB (0.49) | MCHR1TMEM97SIGMAR1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11464568 | 0.79 | SMN1; SMN2 (0.48) | MCHR1TMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL8532312 | 0.79 | SIGMAR1 (0.48) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| Hydrochloric Acid SCHEMBL11453416 | 0.76 | POLB (0.46) | MCHR1TMEM97SIGMAR1ADRA2AADRA2B | |
| SCHEMBL5582800 | 0.75 | MCHR1 (0.52) | MCHR1HTR2C | |
| SCHEMBL15093971 | 0.71 | CYP2A13 (0.49) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8535295 | 0.71 | SIGMAR1 (0.50) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL15265439 | 0.70 | AGXT (0.56) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 | |
| SCHEMBL18634226 | 0.70 | CYP2C9 (0.41) | TMEM97SIGMAR1ADRA2AADRA2BDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847159-A | 1- ω-(3,4-dihydro-2-naphthalenyl)alkyl!-cyclic amine derivatives, process for preparing the same, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |