SCHEMBL8535317

SCHEMBL8535317

CCC(N)c1ccc(P(c2ccc(C(N)CC)cc2)c2ccc(C(N)CC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.55
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 2/20 0.34
SLC2A1 P11166 1/20 0.33
TDP1 Q9NUW8 3/20 0.32
CYP3A4 P08684 2/20 0.32
LMNA P02545 1/20 0.32
ESR1 P03372 1/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
AR P10275 1/20 0.32
MAPT P10636 1/20 0.32
CHRM1 P11229 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
DRD1 P21728 1/20 0.32
TBXA2R P21731 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23092069 0.85 SLC6A4 (0.70) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL8531230 0.83 SLC2A1 (0.41) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL8286101 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL238408 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1
SCHEMBL8284225 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL3865060 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL8285910 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL3863807 0.76 SLC6A4 (0.59) SLC6A4CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL390989 0.74 SLC6A4 (0.57) SLC6A4CYP2D6CYP2C19TDP1LMNA
SCHEMBL22084231 0.74 SLC6A4 (0.57) SLC6A4CYP1A2CYP2D6CYP2C19SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789551-A4 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1998-12-02 EP claimed
EP-0789551-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU, John R. (US) 1997-08-20 EP claimed
WO-1997011672-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1997-04-03 WO claimed
EP-0789551-A4 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1998-12-02 EP disclosed
EP-0789551-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU, John R. (US) 1997-08-20 EP disclosed
WO-1997011672-A1 HAIR CARE PERMING AGENTS AND PROCESSES LAU JOHN R (US) 1997-04-03 WO disclosed