SCHEMBL8535513

SCHEMBL8535513

CNC(=O)C(=NOC)c1ccccc1C1ON=C1Cc1ccc(C2CCCc3c(OC)cccc32)cc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 5/20 0.39
TAS1R1 Q7RTX1 5/20 0.39
TAS1R2 Q8TE23 3/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
ACHE P22303 1/20 0.37
KDM4C Q9H3R0 1/20 0.36
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8539119 0.88 HAO1 (0.40) TAS1R3TAS1R1TAS1R2
SCHEMBL8539630 0.86 HAO1 (0.34) TAS1R3TAS1R1TAS1R2
SCHEMBL8537723 0.77 HAO1 (0.38) TAS1R3TAS1R1TAS1R2
SCHEMBL8529279 0.68 HIF1A (0.45)
SCHEMBL8529479 0.67 MAPK1 (0.47)
SCHEMBL8528200 0.67 CA1 (0.45) TAS1R3TAS1R1TAS1R2CA1CA2
SCHEMBL8528202 0.67 CA1 (0.45) TAS1R3TAS1R1TAS1R2CA1CA2
SCHEMBL8528868 0.66 CA1 (0.47) TAS1R3TAS1R1TAS1R2CA1CA2
SCHEMBL8526565 0.66 KMT2A (0.42) TAS1R3TAS1R1
SCHEMBL8463915 0.65 KDM4E (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877730-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1998-11-18 EP disclosed
WO-1997016413-A1 ARYL ACRYLICS FOR USE AS FUNGICIDE MONSANTO COMPANY (US) 1997-05-09 WO disclosed