Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539119 | 0.88 | HAO1 (0.40) | HAO1MAPK1MAPK14ALDH1A1GID4 | |
| SCHEMBL8539630 | 0.83 | HAO1 (0.34) | HAO1MAPK1MAPK14ALDH1A1MEN1 | |
| SCHEMBL8535513 | 0.77 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8529014 | 0.75 | MAPK1 (0.38) | HAO1MAPK1MAPK14ALDH1A1GID4 | |
| SCHEMBL8529479 | 0.71 | MAPK1 (0.47) | HAO1MAPK1MAPK14ALDH1A1GID4 | |
| SCHEMBL8821308 | 0.68 | HAO1 (0.36) | HAO1MAPK1MAPK14ALDH1A1CNR1 | |
| SCHEMBL8526565 | 0.66 | KMT2A (0.42) | HAO1MAPK1MAPK14GID4MEN1 | |
| SCHEMBL8528118 | 0.65 | HIF1A (0.46) | HAO1MAPK1MAPK14KDM4E | |
| SCHEMBL7083547 | 0.63 | HAO1 (0.64) | HAO1MAPK1MAPK14ALDH1A1GID4 | |
| SCHEMBL8539648 | 0.63 | HAO1 (0.30) | HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877730-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997016413-A1 | ARYL ACRYLICS FOR USE AS FUNGICIDE | MONSANTO COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |