⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535547 | 1.00 | — | — | |
| SCHEMBL13637170 | 0.73 | — | — | |
| SCHEMBL2365875 | 0.70 | — | — | |
| SCHEMBL2369418 | 0.70 | — | — | |
| SCHEMBL2365869 | 0.70 | — | — | |
| SCHEMBL3924875 | 0.70 | — | — | |
| SCHEMBL1488846 | 0.69 | CHRNA7 (0.33) | — | |
| SCHEMBL17589072 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL15209958 | 0.69 | — | — | |
| SCHEMBL3290650 | 0.69 | HTT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801249-A | Chiral auxiliaries | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1998-09-01 | — | — | US | claimed |
| WO-1995018112-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1995-07-06 | — | — | WO | claimed |
| US-10729688-B2 | Hepatitis B antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190321360-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2019-10-24 | — | — | US | disclosed |
| WO-2019191166-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-03 | — | — | WO | disclosed |
| US-5801249-A | Chiral auxiliaries | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1998-09-01 | — | — | US | disclosed |
| EP-0736017-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018112-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1995-07-06 | — | — | WO | disclosed |