⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535547 | 0.70 | — | — | |
| SCHEMBL8535544 | 0.70 | — | — | |
| SCHEMBL2365875 | 0.65 | — | — | |
| SCHEMBL2365869 | 0.65 | — | — | |
| SCHEMBL2369418 | 0.65 | — | — | |
| SCHEMBL17589072 | 0.64 | ALDH1A1 (0.31) | — | |
| SCHEMBL3290650 | 0.64 | HTT (0.34) | — | |
| SCHEMBL15209953 | 0.64 | — | — | |
| SCHEMBL15209958 | 0.64 | — | — | |
| SCHEMBL15864225 | 0.63 | DUT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075150-B | Method for preparing chiral amino alcohol derivative by asymmetric hydrocarbon bond amination under nonmetal catalysis | 浙江大学 | 2023-06-16 | — | — | CN | disclosed |
| CN-114075150-A | Method for preparing chiral amino alcohol derivative through nonmetal-catalyzed asymmetric carbon-hydrogen bond amination | 浙江大学 | 2022-02-22 | — | — | CN | disclosed |
| US-7488818-B2 | Method for producing 1,4-diphenyl azetidinone derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-02-10 | — | — | US | disclosed |
| EP-1756049-B1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-20070149776-A1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-06-28 | — | — | US | disclosed |
| EP-1756049-A1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005113496-A1 | METHOD FOR PRODUCING 1,4-DIPHENYL AZETIDINONE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (US) | 2005-12-01 | — | — | WO | disclosed |