Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496223 | 0.82 | CNR1 (0.53) | PPARAPPARGCYP2D6CNR1CNR2 | |
| SCHEMBL8499366 | 0.82 | CNR1 (0.53) | PPARAPPARGCYP2D6CNR1CNR2 | |
| SCHEMBL8497043 | 0.82 | ATM (0.61) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8500276 | 0.82 | ATM (0.61) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8538236 | 0.82 | ATM (0.61) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8533964 | 0.80 | ATM (0.77) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8499131 | 0.80 | ALDH1A1 (0.71) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8499822 | 0.78 | HTT (0.69) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL903628 | 0.78 | ATM (0.68) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8538203 | 0.78 | ATM (0.68) | ATMMEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |