Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538203 | 1.00 | ATM (0.68) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL12949944 | 0.96 | ATM (0.64) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8533964 | 0.95 | ATM (0.77) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL12949880 | 0.94 | ATM (0.60) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL16919227 | 0.92 | ATM (0.57) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8538518 | 0.91 | ALDH1A1 (0.66) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8534491 | 0.91 | ATM (0.70) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL14722412 | 0.90 | HTT (0.58) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL17427770 | 0.89 | PKM (0.60) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8538236 | 0.89 | ATM (0.61) | ATMMEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964210-B1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LTD (IN) | 2023-10-04 | — | — | EP | claimed |
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | claimed |
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LIMITED (IN) | 2016-01-14 | — | — | US | claimed |
| EP-2964210-A2 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | Biocon Limited (IN) | 2016-01-13 | — | — | EP | claimed |
| WO-2014136047-A2 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LIMITED (IN) | 2014-09-12 | — | — | WO | claimed |
| EP-2964210-B1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LTD (IN) | 2023-10-04 | — | — | EP | disclosed |
| EP-2896609-B1 | Crystalline fingolimod citrate for the treatment of relapsing-remitting multiple sclerosis | RATIOPHARM GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | disclosed |
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | disclosed |
| EP-2807143-B1 | PROCESS FOR PREPARATION OF FINGOLIMOD | GLENMARK GENERICS LTD (IN) | 2017-08-30 | — | — | EP | disclosed |
| EP-1457478-B1 | Production of 2-amino-2-[2-(4-alkyl-phenyl)ethyl]propane-1,3-diols | NOVARTIS AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9643914-B2 | Fingolimod hydrochloride process | EMCURE PHARMACEUTICALS LIMITED (IN) | 2017-05-09 | — | — | US | disclosed |
| EP-0778263-B1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | WELFIDE CORP (JP) | 2002-01-09 | — | — | EP | disclosed |
| EP-1129066-A1 | PRODUCTION OF 2-AMINO-2- 2-(4-C 2-20?-ALKYL-PHENYL)ETHYL]PROPANE-1,3-DIOLS | Novartis AG (CH) | 2001-09-05 | — | — | EP | disclosed |
| US-6187821-B1 | SUCH AS 2-AMINO-2-(3-(4-HEPTYLPHENYL)PROPYL)BUTANE-1,4-DIOL; IMMUNOSUPPRESSANT; ADMINISTERING TO TREAT OR PREVENT AUTOIMMUNE DISEASES AND ALLERGIES | WELFIDE CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| WO-2000027798-A1 | PRODUCTION OF 2-AMINO-2-[2-(4-C2-20-ALKYL-PHENYL)ETHYL]PROPANE-1,3-DIOLS | NOVARTIS AG (CH) | 2000-05-18 | — | — | WO | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0778263-A1 | BENZENE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | ADH1C, DRD2, ADH1A | ATM 1912/4885MEN1 2875/4885MAPT 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.