Glycerin

Glycerin

SCHEMBL8535610

CC(S)C(=O)O.OCC(O)CO

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
ALDH1A1 P00352 3/20 0.47
OR51E2 Q9H255 1/20 0.43
TP53 P04637 1/20 0.43
RNPEP Q9H4A4 1/20 0.42
ACE P12821 1/20 0.39
TDP1 Q9NUW8 4/20 0.38
MAPT P10636 2/20 0.38
PTGS2 P35354 1/20 0.38
HPGD P15428 2/20 0.36
HSD17B10 Q99714 2/20 0.36
ABCB11 O95342 1/20 0.36
F2 P00734 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
DUSP3 P51452 1/20 0.36
PTPN5 P54829 1/20 0.36
PTPN11 Q06124 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL5029753 1.00 LMNA (0.47) LMNAALDH1A1OR51E2TP53RNPEP
SCHEMBL6004245 0.88 OR51E2 (0.39) LMNAALDH1A1OR51E2TP53RNPEP
Propylene Glycol SCHEMBL1171003 0.86 TDP1 (0.56) LMNAALDH1A1OR51E2TP53RNPEP
Glycerin SCHEMBL1838800 0.83 LMNA (0.53) LMNAALDH1A1OR51E2TP53TDP1
Glycerin SCHEMBL7795652 0.83 LMNA (0.53) LMNAALDH1A1OR51E2TP53RNPEP
Lactic Acid SCHEMBL4527725 0.83 TP53 (0.65) LMNAALDH1A1OR51E2TP53TDP1
Glycerin SCHEMBL2442337 0.83 LMNA (0.53) LMNAALDH1A1OR51E2TP53TDP1
Lactic Acid SCHEMBL15512248 0.83 TP53 (0.65) LMNAALDH1A1OR51E2TP53TDP1
Glycerin SCHEMBL11364524 0.83 LMNA (0.53) LMNAALDH1A1OR51E2TP53TDP1
Lactic Acid SCHEMBL320231 0.83 TP53 (0.65) LMNAALDH1A1OR51E2TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0638550-B1 Method for extracting malodorous compounds present in a formulation containing at least one compound with a thiol group and deodorised compositions thus obtained OREAL (FR) 1998-01-07 EP claimed
EP-0622109-B1 Process for deodorizing a formulation comprising at least one compound bearing a thiol group OREAL (FR) 1997-07-30 EP claimed
US-5458848-A Deodorizing L'OREAL (FR) 1995-10-17 US claimed
US-5458848-A Deodorizing L'OREAL (FR) 1995-10-17 US disclosed