Glycerin

Glycerin

SCHEMBL7795652

O=C(O)C(S)S.OCC(O)CO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 2/20 0.53
OR51E2 Q9H255 1/20 0.48
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ABCB11 O95342 1/20 0.40
F2 P00734 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
KMT2A Q03164 1/20 0.40
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
CYP2C9 P11712 1/20 0.40
HIF1A Q16665 1/20 0.40
PDE4A P27815 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monothioglycerol SCHEMBL812749 0.87 LMNA (0.65) LMNAALDH1A1OR51E2HPGDHSD17B10
Glycerin SCHEMBL8535610 0.83 LMNA (0.47) LMNAALDH1A1OR51E2HPGDHSD17B10
Glycerin SCHEMBL5029753 0.83 LMNA (0.47) LMNAALDH1A1OR51E2HPGDHSD17B10
Dihydroxyacetone SCHEMBL574146 0.81 LMNA (0.60) LMNAALDH1A1OR51E2TDP1KDM4E
Glycerin SCHEMBL30929982 0.81 LMNA (0.69) LMNAALDH1A1OR51E2TDP1PDE4A
Glycerin SCHEMBL28563108 0.81 LMNA (0.69) LMNAALDH1A1OR51E2TDP1PDE4A
Glycerin SCHEMBL7030045 0.81 LMNA (0.69) LMNAALDH1A1OR51E2TDP1PDE4A
Glycerin SCHEMBL4671978 0.81 LMNA (0.69) LMNAALDH1A1OR51E2TDP1PDE4A
Glycerin SCHEMBL44491 0.81 LMNA (0.69) LMNAALDH1A1OR51E2TDP1PDE4A
Propylene Glycol SCHEMBL17512168 0.80 TDP1 (0.56) LMNAALDH1A1OR51E2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988749-A Discoloration inhibition by adding a sulfur stabilizer and a sulfur plasticizer MONSANTO COMPANY (US) 1991-01-29 US claimed
CN-115135697-A Process for producing polythioether compound 株式会社大赛璐 2022-09-30 CN disclosed
CN-113278149-A Process for producing polythioether compound 株式会社大赛璐 2021-08-20 CN disclosed
US-20010049420-A1 Method for producing hydrocarbon/acrylic hybrid resins WESTVACO CORPORATION (US) 2001-12-06 US disclosed
US-20010008921-A1 Hydrocarbon/acrylic hybrid resins for use as sizing compositions WESTVACO CORPORATION (US) 2001-07-19 US disclosed
US-20010000514-A1 Hydrocarbon/acrylic hybrid resins for use in gravure printing ink formulations WESTVACO CORPORATION (US) 2001-04-26 US disclosed
US-20010000342-A1 Hydrocarbon/acrylic hybrid resins for use in lithographic printing ink formulations WESTVACO CORPORATION (US) 2001-04-19 US disclosed
US-20010000253-A1 Hydrocarbon/acrylic hybrid resins for use in continuous ink jet ink formulations WESTVACO CORPORATION (US) 2001-04-12 US disclosed
EP-1054028-A1 Method for producing hydrocarbon/acrylic hybrid resins WESTVACO CORPORATION (US) 2000-11-22 EP disclosed
US-5216065-A Controlling monomer addition THE MEAD CORPORATION (US) 1993-06-01 US disclosed
EP-0270709-B1 PROCESS FOR THE PRODUCTION OF VINYL POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-02-06 EP disclosed
US-4988749-A Discoloration inhibition by adding a sulfur stabilizer and a sulfur plasticizer MONSANTO COMPANY (US) 1991-01-29 US disclosed
EP-0270709-A1 Process for the production of vinyl polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-15 EP disclosed