Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837176 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL23133333 | 0.85 | TDP1 (0.42) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL6371711 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL23133330 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL26353037 | 0.83 | MAPT (0.46) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL6370055 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL8901563 | 0.81 | PKM (0.48) | ALDH1A1MAPTKDM4ELMNAPKM | |
| SCHEMBL11135612 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL10778338 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPTKDM4ECYP3A4 | |
| SCHEMBL9160180 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | disclosed |
| US-5534036-A | Keratinous fiber dyeing methods and compositions which contain sulfated methaphenylenediamine couplers in combination with oxidation dye precursors | L'OREAL (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0591059-A1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |