Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533378 | 0.88 | PTPN11 (0.46) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8533556 | 0.88 | TAOK3 (0.45) | TP53TSHRPLA2G4BRARBTAOK3 | |
| SCHEMBL8536524 | 0.85 | TP53 (0.40) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8532626 | 0.84 | TAOK3 (0.44) | TP53TSHRPLA2G4BPLA2G4ATAOK3 | |
| SCHEMBL8763749 | 0.83 | S1PR1 (0.52) | TP53TSHRPLA2G4BPLA2G2A | |
| SCHEMBL8536526 | 0.82 | TP53 (0.40) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8763562 | 0.82 | TP53 (0.47) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8777440 | 0.81 | NPC1 (0.41) | TP53TSHRPLA2G4BTAOK3TAOK1 | |
| SCHEMBL7407569 | 0.79 | TP53 (0.52) | TP53TSHRPLA2G4BRARB | |
| SCHEMBL8536738 | 0.79 | PTPN11 (0.53) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776365-A | COMPOUNDS WITH OPTICAL ACTIVITY AND SWITCHES FOR CONTRAST | MITSUI CHEMICALS, INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5725798-A | CARBOXYLIC ESTERS FOR ELECTRICAL APPARATUS, SWITCHES AND CONTRAST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0549347-B1 | Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements | MITSUI PETROCHEMICAL IND (JP) | 1997-10-29 | — | — | EP | disclosed |
| EP-0549347-A1 | Novel carboxylate compounds, liquid crystal materials, liquid crystal compositions and liquid crystal elements | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |