Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114930 | 0.92 | RAB9A (0.56) | SRD5A2KDM4EL3MBTL1NR4A2ALDH1A1 | |
| SCHEMBL503179 | 0.89 | SRD5A2 (0.67) | SRD5A2KDM4EL3MBTL1NR4A2ALDH1A1 | |
| SCHEMBL11844589 | 0.84 | SRD5A2 (0.64) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL25188173 | 0.84 | SRD5A2 (0.64) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL27363308 | 0.84 | SRD5A2 (0.64) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL10994744 | 0.84 | SRD5A2 (0.68) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL2561144 | 0.83 | SRD5A2 (0.62) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL10967373 | 0.83 | SRD5A2 (0.66) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL7786912 | 0.83 | SRD5A2 (0.66) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B | |
| SCHEMBL10968921 | 0.83 | SRD5A2 (0.66) | SRD5A2KDM4EL3MBTL1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |