Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534559 | 0.97 | PDE4A (0.37) | HDAC1HDAC8MEN1KMT2AHTR6 | |
| SCHEMBL8539972 | 0.97 | HDAC1 (0.36) | HDAC1HDAC8MEN1KMT2AHTR6 | |
| SCHEMBL8539163 | 0.96 | MEN1 (0.38) | HDAC1HDAC8MEN1KMT2AHTR6 | |
| SCHEMBL8535546 | 0.93 | PDE4A (0.38) | HDAC1HDAC8MEN1KMT2AHTR6 | |
| SCHEMBL8538749 | 0.93 | MEN1 (0.37) | HDAC1HDAC8MEN1KMT2AHTR6 | |
| SCHEMBL7370592 | 0.92 | HTR6 (0.39) | HDAC1HDAC8HTR6MAP1LC3BMAP1LC3A | |
| SCHEMBL7372608 | 0.89 | HTR6 (0.38) | HDAC1HDAC8HTR6PDE4AMAP1LC3B | |
| SCHEMBL7376434 | 0.89 | HTR6 (0.38) | HDAC1HDAC8HTR6MAP1LC3BMAP1LC3A | |
| SCHEMBL7373124 | 0.88 | HTR6 (0.38) | MEN1KMT2AHTR6MAP1LC3BMAP1LC3A | |
| SCHEMBL7366903 | 0.85 | PTGES (0.37) | MEN1KMT2AHTR6MAP1LC3BMAP1LC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |