Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5821118 | 1.00 | CYP19A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL5821117 | 1.00 | CYP19A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL7276614 | 0.87 | CYP17A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL27484897 | 0.84 | CYP17A1 (0.63) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL6949630 | 0.83 | CYP19A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL11214315 | 0.83 | CYP19A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL5297627 | 0.83 | CYP17A1 (0.82) | CYP19A1CYP17A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL14863192 | 0.81 | CYP19A1 (0.54) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL4578052 | 0.80 | CYP17A1 (0.83) | CYP19A1CYP17A1MEN1NR1I2USP2 | |
| SCHEMBL6977589 | 0.80 | CYP17A1 (0.61) | CYP19A1CYP17A1MEN1NR1I2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060163-C | Acylated aminoalknimidazoles and-triazoles | NORVATIS (CH) | 2001-01-03 | — | — | CN | disclosed |
| EP-0683156-B1 | Acylated aminoalkanimidazoles and -triazoles | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| US-5622982-A | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS | SANDOZ LTD. (CH) | 1997-04-22 | — | — | US | disclosed |
| CN-1120039-A | Acylated aminoalknimidazoles and-triazoles | SANDOZ LTD (CH) | 1996-04-10 | — | — | CN | disclosed |
| EP-0683156-A1 | Acylated aminoalkanimidazoles and -triazoles | SANDOZ LTD. (CH) | 1995-11-22 | — | — | EP | disclosed |