Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 7/20 | 0.58 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312093 | 0.83 | NISCH (0.60) | NISCHMAOBTOP2ATOP2BPTGIR | |
| SCHEMBL5310372 | 0.81 | NISCH (0.56) | NISCHMAOAMAOBTOP2ATOP2B | |
| SCHEMBL1886692 | 0.77 | NISCH (1.00) | NISCHMAOAMAOBTOP2ATOP2B | |
| SCHEMBL8864111 | 0.76 | ALDH1A1 (0.42) | MAOB | |
| SCHEMBL8866488 | 0.74 | AR (0.50) | — | |
| SCHEMBL8141749 | 0.70 | NISCH (1.00) | NISCHMAOAMAOBTOP2ATOP2B | |
| SCHEMBL9575256 | 0.69 | NISCH (1.00) | NISCHPTGIR | |
| SCHEMBL13030877 | 0.68 | NISCH (0.73) | NISCHMAOAMAOBTOP2ATOP2B | |
| SCHEMBL5476725 | 0.68 | NISCH (0.79) | NISCHTOP2ATOP2B | |
| SCHEMBL11462790 | 0.67 | NISCH (1.00) | NISCHMAOAMAOBTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723288-A | Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans, and kits useful therefor | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-03-03 | — | — | US | disclosed |