Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176372 | 0.81 | ADRB2 (0.41) | ALDH1A1SMN1; SMN2LMNATSHRTHRB | |
| SCHEMBL1937796 | 0.81 | — | — | |
| SCHEMBL1935530 | 0.75 | ADRB2 (0.45) | ALDH1A1SMN1; SMN2LMNATSHRTHRB | |
| SCHEMBL6433585 | 0.73 | — | — | |
| 1,4-Butanediol SCHEMBL1356092 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNATSHRMEN1 | |
| SCHEMBL5342 | 0.73 | — | — | |
| SCHEMBL6178131 | 0.73 | THRB (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6437594 | 0.72 | — | — | |
| SCHEMBL223572 | 0.70 | — | — | |
| SCHEMBL854543 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750343-A | Methods of detecting nucleic acids with nucleotide probes containing 4'-substituted nucleotides and kits therefor | SYNTEX INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5446137-A | Substituent selected from linking group containing modifiers such as biotin, reactive groups, nucleic acids, catalysts, DNA intercalators, minor groove binders, clevage agents, and detectable labels | SYNTEX (U.S.A.) INC. (US) | 1995-08-29 | — | — | US | disclosed |