Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537172 | 0.84 | IDO1 (0.36) | TRPV1 | |
| SCHEMBL15075093 | 0.84 | TRPV1 (0.46) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3320921 | 0.83 | TRPV1 (0.44) | TRPV1KCNE1KCNQ1CYP3A4CYP2D6 | |
| SCHEMBL3320924 | 0.83 | TRPV1 (0.44) | TRPV1KCNE1KCNQ1CYP3A4CYP2D6 | |
| SCHEMBL8538245 | 0.81 | ABCB1 (0.46) | KCNE1KCNQ1CYP3A4CYP2D6 | |
| SCHEMBL8536557 | 0.79 | TLR3 (0.49) | TRPV1 | |
| SCHEMBL15086531 | 0.78 | TRPV1 (0.42) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3319434 | 0.77 | KCNE1 (0.44) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL3319440 | 0.77 | KCNE1 (0.44) | TRPV1KCNE1KCNQ1CYP3A4 | |
| SCHEMBL2364748 | 0.71 | CFTR (0.47) | TRPV1KCNE1KCNQ1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |