Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | TLR3 | O15455 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536328 | 0.84 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL8538245 | 0.81 | ABCB1 (0.46) | — | |
| SCHEMBL9141913 | 0.77 | TLR3 (0.43) | TRPV1HTR2BAKR1B1TLR3OPRM1 | |
| SCHEMBL26759016 | 0.73 | MEN1 (0.34) | IDO1HTR2BAKR1B1 | |
| SCHEMBL8515250 | 0.73 | OPRM1 (0.34) | HTR2BAKR1B1TLR3OPRM1OPRK1 | |
| SCHEMBL2176435 | 0.72 | TRPV1 (0.37) | TRPV1HTR2BAKR1B1OPRM1OPRK1 | |
| SCHEMBL4420243 | 0.71 | HDAC3 (0.39) | IDO1TRPV1 | |
| SCHEMBL13499163 | 0.71 | HDAC3 (0.39) | IDO1TRPV1 | |
| SCHEMBL619444 | 0.71 | HDAC3 (0.39) | IDO1 | |
| SCHEMBL3322864 | 0.70 | CFTR (0.35) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719155-A | CARDIOVASCULAR DISORDERS | JAPAN TOBACCO INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0677519-A1 | CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF | Japan Tobacco Inc. (JP) | 1995-10-18 | — | — | EP | disclosed |