Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30646537 | 0.72 | GLS (0.45) | TDP1GLSKMT2ATHRBLMNA | |
| SCHEMBL19022012 | 0.72 | GLS (0.47) | TDP1GLSMEN1KMT2ATHRB | |
| SCHEMBL17102904 | 0.71 | MAPK1 (0.52) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL8535903 | 0.70 | TDP1 (0.40) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL1093819 | 0.69 | GSK3A (0.44) | NLRP3MAPK1THRBLMNAALDH1A1 | |
| SCHEMBL11655565 | 0.68 | TDP1 (0.56) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL19223347 | 0.67 | TDP1 (0.46) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL19009018 | 0.67 | GLS (0.48) | TDP1GLSMEN1KMT2ATHRB | |
| SCHEMBL15710817 | 0.67 | TDP1 (0.50) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL19000038 | 0.67 | PSMB8 (0.45) | TDP1GLSMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668874-B1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| US-5527777-A | TREATMENT OF PROSTATE CANCER, ANTIFERTILITY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| EP-0668874-A1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-30 | — | — | EP | disclosed |
| WO-1992020711-A2 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |