Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823768 | 0.81 | TRPV1 (0.47) | KMT2AMAPTLMNAGAATBXAS1 | |
| SCHEMBL26398365 | 0.74 | GAA (0.43) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL7866877 | 0.72 | HSD17B10 (0.50) | TDP1KMT2ALMNAGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7019349 | 0.70 | HSD17B10 (0.49) | TDP1KMT2ALMNAGAAALDH1A1 | |
| SCHEMBL17102904 | 0.70 | MAPK1 (0.52) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8536338 | 0.70 | NLRP3 (0.39) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7297042 | 0.70 | TBXAS1 (0.51) | MEN1KMT2ANAMPTTBXAS1 | |
| SCHEMBL7742657 | 0.69 | GAA (0.42) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1075053 | 0.68 | GAA (0.46) | TDP1MEN1KMT2AMAPTGAA | |
| SCHEMBL11655565 | 0.67 | TDP1 (0.56) | TDP1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668874-B1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| US-5527777-A | TREATMENT OF PROSTATE CANCER, ANTIFERTILITY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| EP-0668874-A1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-30 | — | — | EP | disclosed |
| WO-1992020711-A2 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |