Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536354 | 1.00 | CCKBR (0.48) | CCKBRTRPV1CCKARALDH1A1HSD17B10 | |
| SCHEMBL9573650 | 0.91 | ALDH1A1 (0.52) | CCKBRCCKARALDH1A1HSD17B10 | |
| SCHEMBL8587556 | 0.86 | CCKBR (0.46) | CCKBRTRPV1CCKARALDH1A1HSD17B10 | |
| SCHEMBL8587562 | 0.86 | CCKBR (0.46) | CCKBRTRPV1CCKARALDH1A1HSD17B10 | |
| SCHEMBL8775239 | 0.85 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL8774186 | 0.85 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL8774004 | 0.85 | CCKBR (0.61) | CCKBRCCKAR | |
| SCHEMBL9573427 | 0.79 | CCKBR (0.61) | CCKBRCCKARALDH1A1HSD17B10 | |
| SCHEMBL9865548 | 0.79 | CCKBR (0.61) | CCKBRCCKARALDH1A1HSD17B10 | |
| SCHEMBL9055117 | 0.78 | CCKBR (0.45) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |