Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.48 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254261 | 0.94 | CHRNA7 (0.48) | CHRNA7GPR119ACACB | |
| SCHEMBL15253290 | 0.92 | GPR119 (0.58) | CHRNA7GPR119ACACB | |
| SCHEMBL8533987 | 0.92 | GPR119 (0.46) | CHRNA7GPR119ACACB | |
| SCHEMBL9265925 | 0.91 | GPR119 (0.44) | CHRNA7GPR119ACACB | |
| SCHEMBL8537175 | 0.88 | GPR119 (0.47) | GPR119ACACB | |
| SCHEMBL9267845 | 0.86 | GPR119 (0.46) | GPR119SCN9A | |
| SCHEMBL8537302 | 0.86 | GPR119 (0.48) | GPR119ACACB | |
| SCHEMBL15253291 | 0.86 | GPR119 (0.46) | GPR119ACACB | |
| SCHEMBL15253208 | 0.86 | GPR119 (0.46) | GPR119ACACB | |
| SCHEMBL15253497 | 0.86 | GPR119 (0.43) | CHRNA7GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000175-B2 | Bicyclic GPR119 modulators | LUPIN LIMITED (IN) | 2015-04-07 | — | — | US | claimed |
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | claimed |
| US-20130245000-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2013-09-19 | — | — | US | claimed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245000-A1 | BICYCLIC GPR119 MODULATORS | GPR119, GPR180, GPBAR1 | CHRNA7 497/4885GPR119 1/4885ACACB 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.