Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579494 | 0.95 | ALDH1A1 (0.38) | ALDH1A1GAAMAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8448655 | 0.91 | GRIN2B (0.39) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8444918 | 0.91 | GRIN2B (0.39) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8435157 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8436042 | 0.90 | SMN1; SMN2 (0.45) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL7457369 | 0.89 | ALDH1A1 (0.39) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL7458366 | 0.88 | ALDH1A1 (0.36) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL7458362 | 0.88 | ALDH1A1 (0.36) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8436455 | 0.88 | GAA (0.40) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL7458116 | 0.88 | ALDH1A1 (0.42) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |