Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436042 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL9574236 | 0.95 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL8578872 | 0.95 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL7458108 | 0.92 | ALDH1A1 (0.42) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8436455 | 0.92 | GAA (0.40) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL7458116 | 0.92 | ALDH1A1 (0.42) | ALDH1A1GAAMAPK1L3MBTL1GRIN2B | |
| SCHEMBL8094981 | 0.91 | ALDH1A1 (0.40) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL8536471 | 0.90 | ALDH1A1 (0.40) | SMN1; SMN2PKMHTTALDH1A1GAA | |
| SCHEMBL7463311 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8438094 | 0.90 | ALDH1A1 (0.44) | SMN1; SMN2PKMHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |