Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810019 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL8536514 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL6347062 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL6812568 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL5889247 | 0.87 | TRPM8 (0.58) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL3023446 | 0.87 | TRPM8 (0.58) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL2577615 | 0.87 | TRPM8 (0.58) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL6330557 | 0.87 | TRPM8 (0.58) | TRPM8CTRB1CTSBTACR1CTSL | |
| SCHEMBL9058446 | 0.87 | KLK5 (0.49) | TRPM8CTRB1CTSBCTSLALDH1A1 | |
| SCHEMBL13534717 | 0.87 | TRPM8 (0.52) | TRPM8CTRB1CTSBCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670305-B1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORP (JP) | 1998-05-20 | — | — | EP | claimed |
| US-5744630-A | Method of producing 3-amino-2-hydroxy-1-propanol derivatives | KANEKA CORPORATION (JP) | 1998-04-28 | — | — | US | claimed |
| EP-0670305-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORPORATION (JP) | 1995-09-06 | — | — | EP | claimed |
| EP-0670305-B1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORP (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5744630-A | Method of producing 3-amino-2-hydroxy-1-propanol derivatives | KANEKA CORPORATION (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0670305-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXY-1-PROPANOL DERIVATIVE | KANEKA CORPORATION (JP) | 1995-09-06 | — | — | EP | disclosed |