Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535701 | 0.99 | CYP19A1 (0.51) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8531164 | 0.97 | CYP19A1 (0.49) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8531749 | 0.94 | CYP19A1 (0.52) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8531854 | 0.84 | CYP19A1 (0.60) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8532071 | 0.82 | ACHE (0.52) | CYP19A1HTR2CKMT2AACHEALDH1A1 | |
| SCHEMBL8536549 | 0.81 | CYP19A1 (0.58) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8536631 | 0.80 | HTR2C (0.52) | CYP19A1HTR2CKMT2AACHEALDH1A1 | |
| SCHEMBL7166102 | 0.80 | CYP19A1 (0.57) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL8535560 | 0.79 | CYP19A1 (0.62) | CYP19A1KDM4ELMNAPOLBMAPT | |
| SCHEMBL9343214 | 0.79 | CYP19A1 (0.61) | CYP19A1KDM4ELMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825180-A1 | 1-OMEGA-(3,4-DIHYDRO-2-NAPHTHALENYL)ALKYL] CYCLIC AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |