Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 4/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523946 | 0.77 | GABBR2 (0.42) | GABBR2GABBR1TDP1POLBSMN1; SMN2 | |
| SCHEMBL999043 | 0.72 | GABBR2 (0.38) | GABBR2GABBR1LMNATDP1SLC22A6 | |
| SCHEMBL999962 | 0.67 | GABBR2 (0.42) | GABBR2GABBR1LMNATDP1POLB | |
| SCHEMBL999007 | 0.65 | GABBR2 (0.46) | GABBR2GABBR1SMN1; SMN2CYP2C19CYP2D6 | |
| SCHEMBL1171114 | 0.64 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C19CYP2D6 | |
| Hydrogen Sulfide SCHEMBL28282419 | 0.63 | GABBR2 (0.52) | GABBR2GABBR1LMNACYP2C19CYP2D6 | |
| SCHEMBL989866 | 0.61 | CA2 (0.43) | GABBR2GABBR1LMNATDP1CYP2C9 | |
| SCHEMBL2185446 | 0.60 | — | — | |
| Ethylene Glycol SCHEMBL1170971 | 0.60 | GABBR2 (0.48) | GABBR2GABBR1LMNACYP2C19CYP2D6 | |
| SCHEMBL3007536 | 0.60 | MME (0.42) | SMN1; SMN2CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | claimed |