Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.34 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | POR | P16435 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | BCHE | P06276 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethofumesate SCHEMBL29355311 | 1.00 | CA2 (0.37) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL5475440 | 1.00 | CA2 (0.37) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL55264 | 1.00 | CA2 (0.37) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL27295007 | 0.96 | ALDH1A1 (0.36) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL20267522 | 0.94 | CA2 (0.34) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL7170449 | 0.94 | CA2 (0.34) | CA2CA5AKDM4EMAPTLMNA | |
| Ethofumesate SCHEMBL28190725 | 0.93 | PPARA (0.35) | CA2CA5AKDM4EMAPTLMNA | |
| SCHEMBL11625186 | 0.90 | KDM4E (0.36) | CA2CA5AKDM4EMAPTLMNA | |
| SCHEMBL11254527 | 0.90 | ALPI (0.38) | CA2ALPLALPINQO1POR | |
| SCHEMBL11419854 | 0.89 | CA2 (0.34) | CA2ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
| US-5013353-A | Herbicidal method using diflufenican | MAY & BAKER LIMITED (GB) | 1991-05-07 | — | — | US | disclosed |