Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557081 | 0.88 | PAX8 (0.60) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10461602 | 0.88 | KCNH2 (0.56) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10460949 | 0.86 | KCNH2 (0.73) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10461612 | 0.86 | KCNH2 (0.57) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10461458 | 0.85 | KCNH2 (0.53) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10461861 | 0.84 | KCNH2 (0.70) | KCNH2MEN1PAX8 | |
| SCHEMBL10461068 | 0.84 | MAPT (0.57) | KCNH2MEN1PAX8HRH1 | |
| SCHEMBL10460576 | 0.82 | KCNH2 (0.85) | KCNH2MEN1PAX8HRH1 | |
| Oxalic Acid SCHEMBL10461512 | 0.82 | KCNH2 (0.67) | KCNH2MEN1PAX8KDM4E | |
| SCHEMBL10460508 | 0.82 | KCNH2 (0.64) | KCNH2MEN1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508334-B1 | Novel aminophenol derivatives and pharmaceutical compositions thereof | GREEN CROSS CORP (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | disclosed |