Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048116 | 0.83 | KMT2A (0.58) | SMN1; SMN2LPAR1CA12CA1CA2 | |
| SCHEMBL9435674 | 0.83 | KMT2A (0.63) | SMN1; SMN2LPAR1KMT2AMEN1LMNA | |
| SCHEMBL462304 | 0.82 | LPAR1 (0.66) | SMN1; SMN2LPAR1KMT2AMEN1TDP1 | |
| SCHEMBL9559085 | 0.81 | P2RY1 (0.58) | CA12CA1CA2CA9 | |
| SCHEMBL5642336 | 0.79 | MDM2 (0.59) | SMN1; SMN2LPAR1KMT2AMEN1LMNA | |
| SCHEMBL545945 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL9723517 | 0.76 | KMT2A (0.61) | SMN1; SMN2LPAR1KMT2AMEN1TDP1 | |
| SCHEMBL9463141 | 0.74 | SMN1; SMN2 (0.70) | SMN1; SMN2KMT2AMEN1TDP1LMNA | |
| SCHEMBL17976392 | 0.74 | ABAT (0.61) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8919908 | 0.74 | ALDH1A1 (0.58) | KMT2APLGKLK1KLK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801178-A | ACAT INHIBITOR, ARTERIOSCLEROSIS | NIPPON SHOJI KAISH LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0726247-B1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0726247-A1 | Aniline derivatives having a polyunsaturated fatty acid residue and use thereof | NIPPON SHOJI KAISHA, LIMITED (JP) | 1996-08-14 | — | — | EP | disclosed |