Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462304 | 0.89 | LPAR1 (0.66) | KMT2ALMNALPAR1SMN1; SMN2MEN1 | |
| SCHEMBL28757102 | 0.88 | SMN1; SMN2 (0.57) | KMT2ALMNALPAR1SMN1; SMN2TP53 | |
| SCHEMBL12048116 | 0.87 | KMT2A (0.58) | KMT2ALMNALPAR1SMN1; SMN2EPHX1 | |
| SCHEMBL5642336 | 0.85 | MDM2 (0.59) | KMT2ALMNALPAR1SMN1; SMN2RAB9A | |
| SCHEMBL8536693 | 0.83 | SMN1; SMN2 (0.51) | KMT2ALMNALPAR1SMN1; SMN2MEN1 | |
| SCHEMBL9723517 | 0.82 | KMT2A (0.61) | KMT2ALMNALPAR1SMN1; SMN2MEN1 | |
| SCHEMBL9723538 | 0.81 | KMT2A (0.60) | KMT2ALMNALPAR1SMN1; SMN2MEN1 | |
| SCHEMBL8845511 | 0.80 | KMT2A (0.68) | KMT2ALMNALPAR1SMN1; SMN2MEN1 | |
| SCHEMBL9504118 | 0.79 | LMNA (0.58) | KMT2ALMNALPAR1 | |
| SCHEMBL9723484 | 0.78 | KMT2A (0.57) | KMT2ALMNALPAR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113444024-A | Method for synthesizing polysubstituted ureas, thioureas, chiral ureas and thioureas compounds without catalyst and solvent | 安徽师范大学 | 2021-09-28 | — | — | CN | claimed |
| CN-113444024-A | Method for synthesizing polysubstituted ureas, thioureas, chiral ureas and thioureas compounds without catalyst and solvent | 安徽师范大学 | 2021-09-28 | — | — | CN | disclosed |
| US-9663452-B2 | Method for preparing formamidines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-30 | — | — | US | disclosed |
| US-9663452-B2 | Method for preparing formamidines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-30 | — | — | US | disclosed |
| US-20150266813-A1 | Method For Preparing Formamidines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-09-24 | — | — | US | disclosed |
| US-20150266813-A1 | Method For Preparing Formamidines | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-09-24 | — | — | US | disclosed |
| WO-2014057466-A1 | METHOD FOR PREPARING FORMAMIDINES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-04-17 | — | — | WO | disclosed |
| US-5283362-A | Reacting with an amine, terminating the reaction before the formation of by-product | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1994-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266813-A1 | Method For Preparing Formamidines | PFAS, CYP4F3, CYP2F1 | KMT2A 1822/4885LMNA 1592/4885LPAR1 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.