Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868427 | 0.88 | GAA (0.69) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL26131133 | 0.88 | GAA (0.44) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL9068875 | 0.86 | GAA (0.67) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL20078430 | 0.86 | POLB (0.59) | POLBGAANPC1RAB9AALDH1A1 | |
| SCHEMBL8538092 | 0.85 | ALDH1A1 (0.50) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL1851070 | 0.85 | ALDH1A1 (0.58) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL1854865 | 0.84 | ALDH1A1 (0.51) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL8490121 | 0.84 | ALDH1A1 (0.55) | POLBGAANPC1MAPTRAB9A | |
| SCHEMBL16638707 | 0.83 | POLB (0.68) | POLBGAANPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8464515 | 0.83 | ALDH1A1 (0.50) | POLBGAANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708128-A | HEAT RESISTANCE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-13 | — | — | US | disclosed |