Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7179602 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL9851869 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL4620547 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL8167693 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| Zinc Ion SCHEMBL9576792 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL23581912 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL8469078 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL4617592 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL7519425 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 | |
| SCHEMBL4620045 | 0.96 | CA2 (0.55) | CA2CA1GPR84FFAR1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622404-B1 | Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester | ASAHI DENKA KOGYO KK (JP) | 1998-07-08 | — | — | EP | disclosed |
| EP-0622404-A1 | Crystalline synthetic resin composition containing a group III or IV metal salt of a cyclic organophosphoric ester | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1994-11-02 | — | — | EP | disclosed |